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The Feline Tritrichomonas Project · operations sheet · 27 Oct 2026

Shelter intake & outbreak checklist — feline trichomonosis

Tritrichomonas foetus / blagburni. For the person who has to make placement, staffing and budget decisions. This is not a clinical protocol — drug decisions, doses and monitoring belong to your shelter veterinarian.

1 · On intake — record these, every cat

Roughly a quarter of positive cats in sanctuary-type populations have completely normal stool. A clean-looking cat is not therefore clear, and stool appearance cannot rule the infection in or out.

2 · Sampling

3 · Isolation: test status and symptom status are different axes

StatusAction
Positive, symptomaticIsolate; veterinary treatment decision; separate tray, scooper, gloves; hold through treatment and retest.
Positive, asymptomaticTreat as a carrier. Isolate from negative cats or house only with disclosed positives; do not adopt into a multi-cat home without disclosure.
Negative, symptomaticStill isolate: PCR is ≈94% sensitive, so a single negative does not exclude. Retest or investigate other causes.
Untested, exposedAssume positive for management purposes — separate resources, no shared trays, no mixing with negative cats.

Where control keeps failing despite good hygiene, treating all in-contact cats regardless of result is a recognized fallback — it trades drug exposure in healthy cats for the carriers a test misses. That trade-off is a veterinary decision, made in writing.

4 · Litter and environment — the cheapest lever you have

There is no cyst stage, and the organism survives only days in moist stool. Remove stool promptly and disinfect second. Scooping four times a day beats deep-cleaning once a week; enough trays that no cat queues at a soiled box beats both. Impermeable surfaces, daily tray changes, separate scoops per group. Routine disinfectants are adequate — this is not a panleukopenia protocol.

5 · The medication is a staff-safety item

6 · What the adopter is told, in writing, with dates

“Tested for Tritrichomonas by PCR on ____________ using a ____________ sample. Result: ____________. Treated from __________ to __________. Retested on __________: ____________. A negative retest does not by itself establish clearance — relapse has been reported up to 20 weeks after the last dose — so ____________ may still be a carrier. The diarrhea may return, and a multi-cat household carries a risk.”

If clearance was not confirmed, say so. Ambiguity here is what damages trust later, and it is what puts the adopter's other cats at risk.

7 · The budget decision, stated honestly

Budget for a second course in roughly one in four treated cats, and for the holding time: about 14 days of treatment, then a retest, then a clearance window you can afford. Drug availability has been an international supply problem, not a local one. For a rescue with limited funds, litter management plus adoption disclosure prevents more downstream transmission than treating a handful of cats and re-exposing them to an uncleared population. A cat whose diarrhea settled but who was never confirmed clear is a carrier until proven otherwise.

Isolation welfare: treat the isolation space as a space, not a cage — a hiding place, vertical space, food, water and litter kept apart, something to do, and daily human contact that is not only the moment of dosing. Cats deteriorate in bare cages, and it is easy to get wrong on a busy shift.

Sources

  1. Gookin JL, Hanrahan K, Levy MG. The conundrum of feline trichomonosis. J Feline Med Surg 2017;19:261–274.
  2. Hedgespeth BA, Stauffer SH, Gookin JL. Fecal sample collection technique and treatment history with T. foetus PCR results in 1,717 cats. J Vet Intern Med 2020;34:734–741.
  3. Prevalence of enteropathogens in cats with and without diarrhea in four management models for unowned cats in the southeast United States. PMC7110508.
  4. ABCD. Guideline for trichomonosis. abcdcatsvets.org.
  5. Tritrichomonas foetus: what shelters need to know. Maddie's Shelter Medicine Program, Cornell University.
  6. AVMA recalls and safety alerts — ronidazole for veterinary compounding use.
Not veterinary advice and not a clinical protocol. Operational summary only; drug decisions belong to your shelter veterinarian. Reviewer of record: pending
tritrichomonasproject.org/print/shelter-intake