The Feline Tritrichomonas Project Better outcomes for cats
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Photo: Luna, Highlander · With All My Love Cattery, Texas
Tritrichomonas foetus · Tritrichomonas blagburni

The diarrhea lasted months.
The tests kept coming back normal.

There is a parasite that lives in a cat's colon and causes chronic, foul‑smelling diarrhea — and it is routinely missed because it looks like Giardia under a microscope. This resource collects everything that is actually known about it, what has changed, and what is still unresolved — written for the person holding the cat, not the parasitologist.

34 publications from the Gookin laboratory · 15 first-authored Medical reviewer of record: pending Last verified 26 Oct 2026

Start where you are

Four audiences, one body of evidence. The clinical facts are identical; what changes is what you need to do next.

First, the name

The organism in your cat is still called Tritrichomonas foetus by most veterinarians and virtually every lab. In 2013 a proposal was published to give the feline organism its own species name, Tritrichomonas blagburni, because it is genetically and biologically distinct from the venereal parasite of cattle that shares the name.

That proposal is not universally accepted, and it is used inconsistently: the European cat-disease guidelines use the new name, other international guidance still uses the old one, and Dr. Gookin's own laboratory writes both. They are the same organism. Read the full explanation →

Four numbers that change how you read everything else

Approximate, and they vary by study and by test method — but each one changes a decision.

≈14%
How often a direct fecal smear finds the organism when it is actually there.
A "negative" smear is near-meaningless
≈94%
PCR on a fecal loop sample — roughly twice the yield of a colonic flush.
Why the collection method matters
≈25%
Of confirmed cases still fail the only drug with proven efficacy.
Failure is common, not rare
≤2 yrs
Typical time to spontaneous resolution in untreated cats — treatment may lengthen it.
The finding nobody expects

What most websites still get wrong

The recommended dose of ronidazole was revised downward, and the revision is more than a decade old. Much of the material owners find online still prints the superseded regimen. See the full dosing history →

  1. 2006
    30–50 mg/kg twice daily × 14 days
    Cleared infection in 10 of 10 experimentally infected cats. This is the dose everyone still quotes.
  2. 2011
    half-life measured at 10.5 hours
    Oral absorption was near-complete and the drug was still detectable 48 hours after one dose. Twice-daily dosing was predicted to accumulate.
  3. 2014
    30 mg/kg once daily × 14 daysCurrent
    The authors withdrew the twice-daily recommendation, citing risk of neurological toxicity from accumulation. The revised dose was never itself tested for efficacy — an open gap.
  4. 2024
    auranofin — failed in catsDead end
    A repurposed gold-salt drug killed the organism in the laboratory and did not work in naturally infected cats.
The more we learn about trichomonosis in cats, the more complicated and controversial the infection has become — ranging from what we should call the organism to whether or not we should even bother trying to treat it.
Opening argument of the definitive review — Gookin JL, Hanrahan K, Levy MG. J Feline Med Surg 2017;19:261–274.