The Feline Tritrichomonas Project Better outcomes for cats
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Things that help. And things people try.

Two separate lists, deliberately kept apart on the page: what owners report trying for the infection itself, graded by evidence, and practical supplies that make managing a cat with chronic diarrhea less awful. Most of what follows in the second list has nothing to do with the parasite at all.

Evidence-graded Reviewer of record: pending Last verified 26 Oct 2026
Nothing on this page treats the infection. The items below are management aids. Anything that would be a treatment appears in the first block with an evidence grade, so you can tell the difference at a glance.

How we grade a claim

Every recommendation on this site carries one of four badges. They are the reason a veterinarian can point someone here instead of rolling their eyes, and they are what makes any commerce below defensible.

BadgeWhat it means
Clinical trialStudied in cats with this infection, with an outcome measured.
Laboratory onlyWorked in a dish or a culture. Has not been tested in infected cats.
No published evidenceWidely repeated, never studied. May still be worth doing for other reasons.
Harm reportedThere is published evidence of harm. Avoid.

What owners report trying

This is anecdote, labeled as anecdote. A story is evidence that someone reports an outcome; it is not evidence that the thing caused the outcome. Where the literature and the anecdote disagree, the literature is stated too.

Reported by owners and fosterers
WhatGradeWhat the evidence says
Probiotics (Enterococcus faecium) Laboratory only Inhibited the organism's growth, adhesion and cytotoxicity in vitro. No trial in infected cats has been published. Plausible as prevention; unproven as treatment.
Highly digestible or high-fibre diets No published evidence Commonly recommended for the diarrhea. No trial data for this infection. Frequent switching may worsen the dysbiosis.
Pumpkin, psyllium, fibre supplements No published evidence Frequently reported to firm up stool. Harmless for most cats if introduced gradually. Not a treatment.
Colonic flushing to "clear" the parasite No published evidence Flushing is a sampling technique. It appears in no guideline as therapy.
Metronidazole Does not clear infection Stool firms up while it is given; the diarrhea returns afterwards because the organism is not eliminated.
Paromomycin Harm reported Published acute renal failure in four cats. Do not use.
Have an experience worth adding? Owner and fosterer experiences are the largest body of practical knowledge about this infection that exists anywhere, and almost none of it is published. We collect them with written permission, publish them pseudonymously, and attach the evidence grade to each one. Report your case → · how that works

Make life easier

The unglamorous half. None of this treats anything, and none of it needs to be bought from us — if you already own a kitchen scale and a spare litter tray, you need nothing here.

Affiliate disclosure Some links in this section are affiliate links. If you buy through one, this site earns a small commission at no extra cost to you. It does not change which items are listed, their order, or any evidence grade — and no prescription or supplement product on this site carries an affiliate link. Our evidence ratings are fixed before any commercial relationship exists.
Management supplies
ItemWhy it helps
Digital scale, 1 g resolution
Pet scale ↗
Weight is the single most useful number in this disease. Doses are calculated by weight, and gradual loss is easy to miss on a cat you see daily.
Extra litter trays — one per cat, plus one
Disposable trays ↗ Stainless tray ↗
Reduces queueing at a soiled box, which is the main route of fecal–oral spread in a multi-cat house. Disposable trays matter during a treatment course, when the box itself is a fomite; washable ones are the cheaper answer for the other fifty weeks of the year.
Non-clumping litter
The one we use ↗
Some litters inhibit the PCR reaction, and a loop sample avoids the problem entirely. Useful when you have to send a voided sample — and it is the only sensible default in a house with kittens, who taste things and can swallow clumping clay. Low dust is a bonus when you are scooping twice a day; non-clumping is the part that matters.
Clumping litter, for ordinary weeks
Clumping pick ↗
What most households actually use, and fine day to day. Do not use it for the sample you send — the clumping agent contaminates a voided stool, which is one of the reasons a negative result means so little. Keep a bag of plain non-clumping litter for sampling weeks.
High-sided or covered tray
Covered steel box ↗
Chronic diarrhea plus a low-sided box means stool on the floor, which means paws, which means spread.
Washable waterproof pads
Washable pads ↗
For car trips, vet visits, and the corner the cat has chosen. Cheaper and less stressful than repeated bedding washes.
Enzymatic pet cleaner
Enzymatic cleaner ↗
Ordinary household cleaner does not remove the residue that keeps attracting the cat back to the same spot.
Pet-safe surface disinfectant
Spray ↗ Concentrate ↗
The organism is fragile outside the cat and dies to routine disinfection — the tray, not the furniture, is what needs cleaning. Must be safe around cats, not just effective. Accelerated hydrogen peroxide is the one most shelters use: it is a disinfectant, not a treatment, and it does nothing for a cat that already has the infection.
Nitrile gloves
Non-latex gloves ↗
For anything that involves bare hands and stool: cleaning a tray during a course, bagging a sample, wiping a bottom. Latex-free matters because repeated latex exposure is a common sensitivity in people who clean up after animals all day. It is also the cheapest way to answer the insurance question.
Pop-up isolation pen or spare room setup
Pen panels ↗ Kitten pen ↗
If you need to separate a treated cat from untreated ones while a course finishes, having the kit already is the difference between doing it and not.
Fecal sample kit / collection pots
Sample pots ↗
Bringing a fresh sample on the day of a bad stool materially improves the test result.
Grooming wipes
Pet wipes ↗
Diarrhea on a long-haired cat is a welfare issue, not a cosmetic one.

As an Amazon Associate I earn from qualifying purchases. The links above that end in ↗ go to Amazon and are affiliate links: the price you pay is unchanged, and this site receives a small commission. Items are listed in a fixed order set by usefulness, not by commission rate, and no prescription product, probiotic, supplement or prescription diet on this site carries a link of any kind.

What we will not sell

Probiotics, supplements, prescription diets and anything else whose evidence is graded Laboratory only or No published evidence on this page. A resource cannot simultaneously tell you a category has no clinical evidence and earn a commission recommending it. That constraint is written into the editorial policy rather than left to good intentions.